2027. Popliteal Peripherally Inserted Central Catheter (PICC) Use in Neonates

Abstract

Abstract Background PICCs are widely used in the neonatal intensive care unit (NICU). PICCs play an essential role in providing IV access to maintain administration of fluids, parenteral nutrition (TPN), and antibiotics to premature neonates. Multiple anatomical sites can be used for PICC placement. Complication rates vary depending on the PICC insertion site. There are few published data on the use of Popliteal PICCs (P-PICC) in neonates. Methods We retrospectively reviewed charts of all neonates admitted to a Level III NICU between 1/1/2016 and 12/31/2020 and underwent PICC placement. Demographic data, number of days with PICC (dwell time), and complications were gathered. Complications included infectious and mechanical. These data were compared between P-PICC and non-Popliteal PICCs (NP-PICC) using Chi-square (C), t-test (T), and Mann-Whitney U test (MW). Results A total of 1241 PICCs were inserted in 784 neonates: 126 (10.2%) were P-PICCs and 1115 (89.8%) NP-PICCs. The average dwell time for P-PICCs was 15.4 days compared to 14.2 days for NP-PICCs (p=0.24). P-PICCs were more likely to have complications (11.5%) compared to NP-PICCs (8.7%) (p= 0.039.). Infectious complications for P-PICCs (5.5%) compared to NP-PICCs (3.2%) were significantly higher (p=0.048). For mechanical complications there was no significant difference between P-PICCs (11.5%) vs NP- PICCs (8.7%); (p = 0.17). P-PICCs were more likely to be placed in lower birth weight and lower gestational age neonates compared to NP-PICC group (p< 0.001). Conclusion There was a significant increase in overall complication rate in P-PICCs compared to NP-PICCS. This difference was primarily due to a higher number of infectious complications. The increased complication rate may have been driven by the lower gestational age and birth weight of the neonates. Additional data are needed to confirm this finding. Disclosures All Authors: No reported disclosures.