Abstract
Iodide supply to the developing fetus is dependent on maternal dietary iodine intake and on functioning placental iodine transport; maternal iodine excretion falls precipitously at delivery. The aim of this study was to evaluate iodide uptake, tissue iodine content and transporter expression in placental tissue obtained from women undergoing prelabor cesarean section (CS) at term. The influences of different pregnancy-associated hormones on placental iodine uptake and its relationship to alterations in the expression levels of the iodide transporters, sodium iodide symporter (NIS) and Pendrin (PDS) were also assessed.
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