Abstract

Chlamydia trachomatis serovars/genovars L2b and L2 are the causative strains in the majority of cases in Europe. Among MSM, about 25% of the anorectal LGV infections are asymptomatic. Genital infections among MSM are rare; the ratio of genital vs. anorectal LGV infections is 1 in 15. To diagnose LGV, a sample tested C.trachomatis positive with a commercial nucleic acid amplification test (NAAT) platform should be confirmed with an LGV discriminatory NAAT. Doxycycline 100mg twice a day orally for 21days is the recommended treatment for LGV. This same treatment is recommended also in asymptomatic patients and contacts of LGV patients. If another regimen is used, a test of cure (TOC) must be performed.

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