Abstract
You have accessJournal of UrologyImaging/Radiology: Uroradiology I1 Apr 20102010 REAL-TIME BALLOON INFLATION ELASTOGRAPHY OF PROSTATE MIGHT SURPASS MRI FOR DETECTION OF PROSTATE CANCER Masahiro Sumura, Yozo Mitsui, Naoko Arichi, Takeo Hiraoka, Koji Wake, Satoshi Honda, Hiroaki Yasumoto, Hiroaki Shiina, and Mikio Igawa Masahiro SumuraMasahiro Sumura More articles by this author , Yozo MitsuiYozo Mitsui More articles by this author , Naoko ArichiNaoko Arichi More articles by this author , Takeo HiraokaTakeo Hiraoka More articles by this author , Koji WakeKoji Wake More articles by this author , Satoshi HondaSatoshi Honda More articles by this author , Hiroaki YasumotoHiroaki Yasumoto More articles by this author , Hiroaki ShiinaHiroaki Shiina More articles by this author , and Mikio IgawaMikio Igawa More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.2043AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Although the efficacy of real-time tissue elastography (RTE) for prostate cancer detection has been reported, the procedure is highly operator dependent. We speculated that the use of a pressure device might decrease operator dependency and increase the detection rate of RTE. A pressure device driven water pressure was developed for this study, which we termed real-time balloon inflation elastography (RBIE), and the procedure investigated for its effectiveness in detecting prostate cancer. METHODS From July, 2008 to February, 2009, 87 patients had abnormal digital rectal examination (DRE), PSA, and/ or TRUS findings, and were enrolled in this study. Their median age was 73 years -old (range 54-89), median PSA was 7.6 ng/mL (range 0.8-2606.0), and the median number of biopsy cores obtained from each was 8 (range 8-10). All patients were examined with MRI prior to prostate needle biopsy and a total of 733 specimens obtained by systemic biopsies were studied. The findings of RTE, RBIE, TRUS, PDUS, and MRI [T2WI, dynamic contrast enhanced images imaging (DCEI)] were compared with histopathological findings of the biopsy specimens. RESULTS Prostate cancer was detected in 48 of 87 patients (55.2%), and 178 of 733 specimens (24.3%), of which 49, 56, and 73 specimens had Gleason scores of 5-6, 7, and 8-10, respectively. Clinical stage was T1c, T2a-c, T3a-b, and T4 in 6, 26, 10, and 6 cases, respectively. The sensitivity of RBIE, RTE, TRUS, PDUS, T2WI, and DCEI was 72.5%, 71.9%, 75.8%, 75.8%, 72.5%, and 71.3%, respectively, while specificity was 97.7%, 85.8%, 85.4% 86.6%, 89.7%, and 91.5%, respectively. Sensitivity and specificity of RBIE were both superior to those of MRI. CONCLUSIONS RBIE is known to be a low cost and less invasive procedure, while its prostate cancer detection capability may be superior to that of MRI, which is expensive and time consuming. Izumo, Shimane, Japan© 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 183Issue 4SApril 2010Page: e780 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information Masahiro Sumura More articles by this author Yozo Mitsui More articles by this author Naoko Arichi More articles by this author Takeo Hiraoka More articles by this author Koji Wake More articles by this author Satoshi Honda More articles by this author Hiroaki Yasumoto More articles by this author Hiroaki Shiina More articles by this author Mikio Igawa More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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