Abstract
Genomic imprinting refers to an epigenetic phenomenon that leads to expression of certain genes in a parent-of-origin dependent manner. Altered gene imprinting has been associated with several well-described disorders. One of the underlying molecular mechanisms is uniparental disomy (UPD). Paternal and maternal UPD are frequently associated with clinically distinctive imprinting disorders. For instance, maternal UPD14 is associated with Temple syndrome (TS), whereas paternal UPD14 is associated with Kagami-Ogata Syndrome (KOS).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
