Abstract
The title adamantane derivative, C12H21NO·0.5H2O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential anti-tuberculosis agents. The structure displays intermolecular O—H⋯N, N—H⋯O, O—H⋯O hydrogen bonding and a layered packing structure with distinct hydrophilic and hydrophobic regions. The water molecule lies on a twofold rotation axis.
Highlights
The title adamantane derivative, C12H21NOÁ0.5H2O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential antituberculosis agents
The water molecule lies on a twofold rotation axis
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: HG2403)
Summary
Key indicators: single-crystal X-ray study; T = 173 K; mean (C–C) = 0.002 A; R factor = 0.043; wR factor = 0.112; data-to-parameter ratio = 18.3. The title adamantane derivative, C12H21NOÁ0.5H2O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential antituberculosis agents. The structure displays intermolecular O— HÁ Á ÁN, N—HÁ Á ÁO, O—HÁ Á ÁO hydrogen bonding and a layered packing structure with distinct hydrophilic and hydrophobic regions. The water molecule lies on a twofold rotation axis. Related literature For related literature, see: Bogatcheva et al (2006); du Pont de Nemours and Co. (1969); Lee et al (2003); Tripathi et al (2006) Related literature For related literature, see: Bogatcheva et al (2006); du Pont de Nemours and Co. (1969); Lee et al (2003); Tripathi et al (2006)
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