2-Phenylmalonpiperadide and 2-phenylmalonmorpholide.

Abstract

The structures of 2-phenylmalonpiperadide [systematic name: 2-phenyl-1,3-bis(piperidin-1-yl)propane-1,3-dione, C(19)H(26)N(2)O(2), (I)] and 2-phenylmalonmorpholide [systematic name: 1,3-dimorpholino-2-phenylpropane-1,3-dione, C(17)H(22)N(2)O(4), (II)], have been determined and both their molecular conformations and packing arrangements compared. Although chemically similar, compounds (I) and (II) exhibit different molecular conformations. The only general conformational similarities are that their respective carbonyl groups are orientated in the same direction and the heterocyclic rings exist in the chair arrangement. General similarities in the packing arrangements arise due to both compounds having the same space group (P2(1)2(1)2(1)) and a similar alignment of their phenyl-substituted backbone with respect to the c axis. Similar C-H.O hydrogen-bonding associations are listed for the carbonyl O atoms, while only one of the morpholine O atoms is involved in any such association.