Abstract

Background: More than one-third of clinically node positive (cN+) breast cancer (BC) patients currently show a pathologic complete response (pCR) of the axilla after neoadjuvant systemic therapy (NST). In patients with pCR, axillary lymph node dissection (ALND) is considered as overtreatment. The MARI procedure (Marking Axillary lymph nodes with Radioactive Iodine seeds) combined with pre-NST FDG-PET/CT (MARI protocol) is an accurate method to restage the axilla after NST. Here, we present 3-year follow-up results of BC patients treated according to the MARI protocol.

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