Abstract
In this study, we investigated whether the polymorphism of CYP2C19 affects the formation of active metabolite (AM) of clopidogrel and the antiplatelet effects of the AM in healthy subjects. In this single-dose study, 47 subjects were given 300 mg clopidogrel orally. The mean AUC and Cmax of the AM differed significantly (P
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Schedule a callMore From: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
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