2-D Noninvasive Temperature Measurement of Biological Samples Based on Compressive Thermoacoustic Tomography

Abstract

There is a great need in temperature monitoring in biomedical applications. The current available temperature measurement techniques have some deficiencies in noninvasiveness, applicability, sensitivity and resolution. Microwave-induced thermoacoustic tomography (MITAT) has found diversified applications in biomedical related disciplines. It has been shown that MITAT can be used to estimate the temperature in a noninvasive manner. However, the applicability of the technique is still limited. This work presents experimental demonstration of two-dimensional (2-D) temperature detection of biological samples based on compressive TAT, referred to as MICTAT. Detailed principle of the method is established. A phantom sample and a biological sample are tested by experiments and 2-D temperature maps are obtained. This work provides a new route of getting 2-D temperature maps of biological samples and may find many applications in biomedical related areas.