2:50 PM Abstract No. 102 - Educational Exhibit Tools of the trade: A review of biomaterials used to make guide wires and catheters, and its relevance to the interventional radiologist

Abstract

Learning Objectives Review the various biomaterials used to create guide wires as well as angiographic and indwelling catheters commonly used by interventionalists 2. Compare and contrast these biomaterials across various metrics including biocompatibility, allergenicity, flexibility, radiolucency, and resistance to infection 3. Outline biomaterial considerations in the guide wire and catheter selection process. Background A wide range of biomaterials have been and are currently used to create guide wires and catheters. Each of these materials was created and/or selected based on unique characteristics designed to aid in achieving a desired effect. Biomaterials used for catheters can be divided into derivatives of three broad categories: silicones, latex rubbers, and plastic elastomer. For guide wires, composition of the inner core, outer coil, and coating must be considered. While inner and outer components of guide wires are typically composed of biologically inert metals and metallic alloys; coatings are selected from a wide range of hydrophilic, hydrophobic, and anti-thrombogenic materials. Clinical Findings/Procedure Details The benefits and disadvantages of each catheter material will be discussed. Due to the evolution of angiographic catheters which has led to the increased use of silicone derived materials in recent years, variations within the silicone derivative class will be examined. The composition materials used for guide wires remains varied. These materials will be analyzed based on goal specific performance metrics. Illustrative images will also be presented. Conclusion and/or Teaching Points The types of materials used to create guide wires and catheters is constantly evolving and expanding. A basic knowledge of the biomaterials typically used for catheters and guide wires allows the interventionalist to optimize performance of such devices.