(1R,2R,3R,3'R,4R)-3-[(2-Furyl)hydroxymethyl]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol, a new camphor-based chiral auxiliary

Abstract

Camphor chiral derivatives have proven to be very powerful chiral adjuvants in organic synthesis. The absolute molecular configuration of the title compound, C 15 H 22 O 3 , has been determined due to the chiral character of the (1R)-(+)-camphor. An infinite one-dimensional hydrogen-bonding chain along the [010] direction [O...O 2.747 (3) A] and an intramolecular hydrogen bond [O...O 2.770(3) A] have been found.