1,N6 Ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electro philic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate

Abstract

The labelling of the C-2 and C-5 pair of peaks and the C-8 and C-7 pair of peaks in the NMR spectrum of 1,N6-ethenoadenosine (free base) in Figure 1 were each inadvertently reversed (see reference 26 for the corresponding peaks in the NMR spectrum of the hydrochloride of this base).