Abstract
The first high field 1H NMR spectroscopy studies of the animal brain were performed in 1983 [1]. These studies showed that 1H NMR spectroscopy allows in vivo observation of a number of brain compounds, including different aminoacids, creatine, choline residues, and—under certain perturbations—of lactate. Those initial studies have given rise to a large number of studies which apply 1H NMR spectroscopy to different aspects of brain metabolism, under different kind of perturbations [2]. These studies have shown that a wealth of information can be obtained about cerebral metabolism and physiology by 1H NMR spectroscopy of the animal brain.
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