Abstract

This paper presents design and implementation of a three dimensional magnetic tweezer system for measurement of mechanical and rheological properties of living cells. The developed system consists of a 3D magnetic tweezer (MT) having six magnetic poles, a 3D prove visual measurement system and a control system. To reduce assembling error which causes unnecessary nonlinear error of magnetomotive force estimation, a magnetic pole positioning mechanism was introduced. By exerting a constant static current to each magnetic coil attached to a magnetic pole, effectiveness of the positioning mechanism was experimentally validated with the homogeneity of force amplitude of each pole and agreement of model estimation and measurement result.

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