1942 TREND OF URINARY CONTINENCE STATUS IN PATIENTS SUBMITTED TO RADICAL PROSTATECTOMY AFTER 2 AND 7 YEARS OF FOLLOW UP

Abstract

You have accessJournal of UrologyProstate Cancer: Localized IX1 Apr 20101942 TREND OF URINARY CONTINENCE STATUS IN PATIENTS SUBMITTED TO RADICAL PROSTATECTOMY AFTER 2 AND 7 YEARS OF FOLLOW UP Paolo Puppo, Carlo Introini, Rossana Andreatta, and Angelo Naselli Paolo PuppoPaolo Puppo More articles by this author , Carlo IntroiniCarlo Introini More articles by this author , Rossana AndreattaRossana Andreatta More articles by this author , and Angelo NaselliAngelo Naselli More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.1931AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To compare the urinary continence status at 2 and 7 years in a cohort of patients submitted to radical prostatectomy METHODS Data from 935 subjects submitted to RP performed from 1992 to 2008 were prospectively collected in a computer database. Preoperative PSA, biopsy GS, pathological stage, definitive GS, surgical margin status, continence and erectile function before RP were recorded. Follow up of the subjects consisted basically of physical examination, PSA and urine analysis performed every 3 months the first 2 years, every 6 months in the next 3 years and yearly thereafter. Continence at each follow up visit was assessed by mean the number of pads used by the subject. A subset of patients characterized by a follow up longer than 7 years was selected. Continence status at 2 years follow up was compared to that at 7 years follow up. We identified a group of 122 patients whose continence was unchanged and a group of 17 whose continence worsened. A possible association of certain independent variables with the frequency of their occurrence in the 2 groups was analyzed using the chi square test. The variation of the continence status was evaluated by mean of the Wilcoxon matched-pairs signed-ranks test. RESULTS In all 139 out 935 subjects have a follow up of 7 years or more. At 1 year follow up, 110/139 (79%) did not use any pad, 25/139 (18%) used one pad per day, 4 (3%) two or more pad. At 7 years follow up, 97/139 did not use any pad (70%), 31/139 (22%) one pad, 11 (8%) two or more pads. In 122/139 (87%) continence status was unchanged. In 17 (13%), it worsened. 61/122 (50%) and 10/17 (59%) were 65 years or older at the time of radical prostatectomy. 19/122 (15%) and 3/17 (17%) were submitted to adjuvant or salvage radiotherapy and 44/122 (36%) and 6/17(35%) to hormonal manipulation. 88/122 (72%) and 11/17 (64%) had organ confined prostate cancer. None of the factors examined reached statistical significance. A within comparison of 2 years and 7 years continence status was performed. The deterioration of the continence status, measured in about 13% of the population examined, had a very little chance (p 0.00001) to be a random observation. CONCLUSIONS The urinary continence status worsened in a significant proportion of patients during the observation period, irrespective of age at the time of radical prostatectomy, neoplasm characteristics or of adjuvant or salvage treatments. Genoa, Italy© 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 183Issue 4SApril 2010Page: e754 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information Paolo Puppo More articles by this author Carlo Introini More articles by this author Rossana Andreatta More articles by this author Angelo Naselli More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...