Abstract
[ 18F]Fluoride was produced via the 18O (p, n) 18F reaction using a low volume stainless steel 18O-water target in a small cyclotron. The average 18F production rate for 60 runs was about 720 μCi/μA-min. A typical bombardment time of 20 min produced 120 mCi of 18F-fluoride. [ 18F]2-Fluoro-2-deoxy- d-glucose ([ 18F]2FDG) was prepared using the procedure developed by Tewson [ J. Nucl. Med. 24, 718 (1983)] involving a protected cyclic sulfate glucose derivative as precursor. The routine synthesis and quality testing of [ 18F]2FDG required 1 h and, typically, yields of 30–35 mCi of > 95% HPLC-pure product were obtained.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Radiation Applications & Instrumentation. Part A, Applied Radiation & Isotopes
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
