1870P - Thyroid lobectomy versus total thyroidectomy among early-stage papillary thyroid carcinoma patient

Abstract

BackgroundPapillary carcinoma is the most common type of thyroid cancer and if it is not treated early, it can spread throughout the body. Therefore, the first line of treatment for papillary thyroid cancer is the surgery by removing part of or the entire thyroid. Our study aims to establish the most effective surgical procedure (total thyroidectomy or partial thyroidectomy) to achieve better survival for stage I and II papillary carcinoma and evaluate the effect of the ethnicity, sex and age on patients' survival undergoing these surgical techniques. MethodsWe extracted the data from the Surveillance, Epidemiology, and End Results (SEER) 18 registries. We retrieved data of 3691 patients diagnosed with papillary thyroid cancer in 2010. We evaluated the 5-year overall survival of patients using the log-rank test. Patients were grouped into two groups. The first one underwent thyroid lobectomy (242) and the second underwent total thyroidectomy (3449). Patients were further grouped according to ethnicity (white, black, American or Asian), sex (female or male) and age group. ResultsWe found that total thyroidectomy was associated with better 5-year overall survival rates in patients with early stage papillary carcinoma, compared to lobectomy (98.1% and 96.5%, respectively, P=0.021). Moreover, total thyroidectomy showed better survival rates in females than males (98.6% and 95.7%, respectively, p=0.000) and in young patients aged between 20-39 years (99.8%, p=0.000). Meanwhile, surgical techniques were not significantly associated with patients’ ethnicity. ConclusionsTotal thyroidectomy was superior to lobectomy in early stages papillary thyroid carcinoma. Legal entity responsible for the studySara Ahmed. FundingHas not received any funding. DisclosureAll authors have declared no conflicts of interest.