Abstract

Atezolizumab is a humanized IgG1 monoclonal antibody that targets PD-L1, used in the treatment of different cancer types. A warning has been issued by the European Medicine Agency regarding the risk of Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with atezolizumab. Along with acute generalized exanthematous pustulosis (AGEP) and drug reaction with eosinophilia and systemic symptoms (DRESS), SJS and TEN are classified as severe cutaneous adverse reactions (SCARs).

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