Abstract

Dermal hypersensitivity reaction describes a perivascular infiltrate of lymphocytes with eosinophils. This histology finding does not correspond to any single clinical diagnosis and inconsistent usage of the term ‘dermal hypersensitive reaction’ has led to it becoming a catchall description that most commonly corresponds to the presentations seen with medication reactions, arthropod bites, or urticaria. A 60-year-old woman with insulin-dependent diabetes mellitus and chronic autoimmune thyroiditis has been followed for 12 years after initially presenting with erythematous papules and plaques on the lower back causing severe pruritus.

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