Abstract
Ranitidine, a histamine 2-blocker, is standard of care premedication to prevent hypersensitivity reactions (HSRs) caused by paclitaxel infusion. However, the added value of ranitidine in this premedication regimen is controversial. Therefore, we compared the incidence of clinically relevant HSRs during paclitaxel treatment of a standard premedication regimen including ranitidine with a premedication regimen without ranitidine.
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