185 Predictors of Good Neurologic Outcome Based on the CPC Score (Cerebral Performace Category) in Post Cardiac Arrest Return of Circulation Patients Undergoing Mild Therapeutic Hypothermia and Catheterization: The Importance of Immediate CPR

Abstract

than 50% luminal narrowing). Chi-square tests were used for categorical variables (diabetes, smoking, HTN, hyperlipidemia, gender) and independent T tests for continuous variables (age, CIMT, plaque height). RESULTS: The mean right and left common carotid distal wall CIMT (Group 1 0.82 0.21 mm; Group 2 0.90 0.24 mm) (p 0.017) and the mean plaque height (Group 1 1.75 1.07 mm; Group 2 2.60 0.93 mm) (p 0.001) were significantly higher in Group 2 compared to Group 1. When analyzed by the number of vessels, the General Linear Model was statistically significant (p 0.001). Post hoc analysis with Bonferroni correction showed that the mean CIMT was higher in the groups with multi-vessel disease (greater than 2) compared to Group 1 (p 0.003). There was an increase in CIMT with the number of coronary vessels involved. The mean plaque height was significantly higher in the groups with single, double, triple and quadruple vessel disease compared to Group1 (p 0.001). Logistic regression identified CIMT (p 0.04) and plaque height (p 0.003) as the important factors for predicting CAD. CONCLUSION: Increased CIMT and carotid plaque height are associated with the presence and extent of epicardial coronary stenosis. CIMT may be useful in estimating atherosclerotic burden in multi-vessel disease whereas plaque burden may be more sensitive to detect disease early on in mild CAD (single vessel disease). Carotid ultrasound with plaque quantification may serve as a useful screening tool for the detection of clinically significant CAD.