18341 Comparing safety of blue versus red light illumination in photodynamic therapy using 10% aminolevulinic acid gel on >75-cm2 treatment areas

Abstract

Background: With a growing desire by US dermatologists for field treatment of actinic keratosis (AKs) and patient compliance, photodynamic therapy (PDT) has become an important treatment modality AKs. With blue light illumination in PDT, 10% aminolevulinic-acid gel (ALA gel; Biofrontera) produces fewer local skin reactions (LSR) compared with 20% ALA solution (DUSA). However, it is unclear whether LSR in PDT with ALA gel differs with blue versus red light illumination.