Abstract
We investigated the role of metabolic syndrome (MetS) as an independent risk factor for premature ejaculation (PE), after considering various risk factors of PE. From 2010 Jan to 2016 Aug, records of 1,029 men were analyzed. We performed logistic regression analysis to identify independent risk factors for PE, including covariate of age, marital status, International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF) score, National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) score, Androgen Deficiency in the Aging Male (ADAM) score, serum testosterone levels, and all components of MetS. Acquired PE was defined as self-reported intravaginal ejaculation latency time (IELT) ≤ 3 minute, and MetS was diagnosed by using the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Of 1,029 men, 74 (7.2%) had PE (IELT ≤ 3 min) and 111 (10.8%) had MetS. Multivariate analysis showed that IIEF overall satisfaction score (OR 0.67, P < 0.001), NIH-CPSI pain score (OR 1.07, P = 0.045), NIH-CPSI voiding score (OR 1.18, P = 0.029), and presence of MetS (OR 2.24, P = 0.019) were significantly correlated with prevalence of PE. And also the Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EjD) scores and ejaculation anxiety scores progressively decreased as the number of components of MetS increased.
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