Abstract
Commercially available polidocanol is a US Food and Drug Administration (FDA)–approved sclerosant indicated for the treatment of uncomplicated spider veins and reticular veins in the lower extremities. In contrast, compounded polidocanol are essentially copies of commercially available products. These formulations are not FDA approved and have not undergone review for safety, effectiveness, and quality. Despite restrictions against compounding drugs, polidocanol remains available from compounding pharmacies, potentially exposing patients to series health risks.
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