Abstract
Peptides, composed of amino acids, are developed for topical skin benefits due to their similarity to and effect on the skin’s structural components, such as collagen, elastin, and decorin. A novel acetyl dipeptide (ADP) with known anti-aging, anti-inflammatory, and compromised skin benefits, was further evaluated. RNA was isolated in vitro from full-thickness skin equivalents treated twice for 48 hours with ADP in different formulations. Whole-transcriptome analysis identified differentially expressed genes.
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