1813 EFFICACY AND SAFETY OF PENILE EXTENDER DEVICE IN THE TREATMENT OF THE ACUTE PHASE OF PEYRONIE'S DISEASE:A PILOT STUDY

Abstract

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Peyronie's Disease/Surgical Therapy1 Apr 20111813 EFFICACY AND SAFETY OF PENILE EXTENDER DEVICE IN THE TREATMENT OF THE ACUTE PHASE OF PEYRONIE'S DISEASE:A PILOT STUDY Juan Ignacio Martinez-Salamanca, Alejandra Egui Rojo, Lucia Osorio Cabello, Estefania Linares Espinos, Ignacio Sola Galarza, Claudio Martinez-Ballesteros, and Joaquin Carballido Rodriguez Juan Ignacio Martinez-SalamancaJuan Ignacio Martinez-Salamanca Madrid, Spain More articles by this author , Alejandra Egui RojoAlejandra Egui Rojo Madrid, Spain More articles by this author , Lucia Osorio CabelloLucia Osorio Cabello Madrid, Spain More articles by this author , Estefania Linares EspinosEstefania Linares Espinos Madrid, Spain More articles by this author , Ignacio Sola GalarzaIgnacio Sola Galarza Madrid, Spain More articles by this author , Claudio Martinez-BallesterosClaudio Martinez-Ballesteros Madrid, Spain More articles by this author , and Joaquin Carballido RodriguezJoaquin Carballido Rodriguez Madrid, Spain More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.2185AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES There are a wide range of treatments for the acute phase of Peyronie's disease (PD), but none has proven effective enough to become the standard therefore, leaving its prescription to individual practice. The mechanical traction phenomenon is well known and has potential application in the corporeal fibrosis, tissue retraction and shortening. The aim of this pilot study was to evaluate the efficacy and safety of the use of the penile extender device (PED) in the initial phase of PD. METHODS From Jan 2009 to Sept 2010, 45 pat. with clinical diagnosis of PD in acute phase (evolution period of less than 6 months and pain at rest or with erection) were invited to participate in this prospective pilot study. The following variables were collected: age (years), ° of deviation measured by auto photos (Kelami test) an with ICI, length-girth in stretching and flaccidity status, IIEF-SHIM version, overall satisfaction (OS) 1–100%, pain in erection and flaccid by visual-analogue scale (VAS). Patients were instructed and properly trained to use PED at least 6 h and no more than 8, preventing its use during sleep. Auto photos during erection were carried after 1, 3, 6 and 9 m, comparing the angle of deviation and pat. satisfaction was reassessed at each visit. The Chi-square tests was used to compare discrete factors, t-tests for continuous factors. RESULTS Mean age was 47 years (39–72). The mean curvature was 20–-55° (10°–80°) measured by ICI. The average treatment period was 6 months (4–12 months) the mean reduction in the angle of curvature, measured by Kelami was 45% (15–70%). The average length stretch was 12.4 cm (9–14.5) and flaccidity of 9.5 cm (8.5–12.5). The average length increase was 1.9 cm in stretching and 1.2cm in flaccidity (p>0.05). Mean pre-treatment VAS score was 5.5 and 3.5 at 6 m. Four patients developed erythema in balanopreputial groove that did not require any discontinuation. Mean pre-treatment IIEF-SHIM was (20) and final (after 9 m) of 26.5 (p<0.05). The average OS was 85% (50–90%). Five (14%) out of the 35 pat. included in the study underwent surgery for persisting a curvature > 45° and difficulty for penetration after 9 months of treatment. These patients had a baseline curvature > 60°. CONCLUSIONS In our initial and limited experience, PED seems a safe and effective treatment in terms of overall satisfation, penile curvature as well as pain reduction in the acute phase of PD. After 6 months, statistically sexual function improvement is shown (p<0.05). These results need to be confirmed in further studies. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e728 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Juan Ignacio Martinez-Salamanca Madrid, Spain More articles by this author Alejandra Egui Rojo Madrid, Spain More articles by this author Lucia Osorio Cabello Madrid, Spain More articles by this author Estefania Linares Espinos Madrid, Spain More articles by this author Ignacio Sola Galarza Madrid, Spain More articles by this author Claudio Martinez-Ballesteros Madrid, Spain More articles by this author Joaquin Carballido Rodriguez Madrid, Spain More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...