Abstract

Caffeine therapy improved the pneumocardiogram(PCG) performance of nine infants monitored for prolonged apnea. The patients (BW 1.8+/−0.4 kg, GA 32+/−2 weeks), were examined with a twelve hour PCG at 6.5+/−9.0 weeks of age. Oral caffeine citrate was then started with a loading dose of 20 mg/kg, followed by a daily maintenance dose of 5/mg/kg. A second twelve hour PCG was obtained at 10.0+/−9.0 weeks. All PCG's were read by a computerized analyzer (Medical Graphics). The results of the comparison are shown below:The PCG following caffeine administration showed fewer short (<15 sec) and long apneas (> 15 sec), decreased apnea density, and decreased episodes and percent of PB. Caffeine did not influence number, length, or nadir of associated bradycardias. Caffeine therapy was effective in decreasing the severity of the documented abnormalities in ventilatory control in this group of infants.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.