18-25 Yaş arası genç bireylerdeki melanositik nevüslerin klinik ve dermatoskopik özelliklerinin incelenmesi

Abstract

Background: Melanocytic nevi are common pigmented lesions of the skin. They are sometimes confused with melanoma which is most malign tumor of the skin. Malign transformation of an existing nevus is one of the most seen etiological factor for melanoma formation. Objective: Although characteristics of childhood nevi well studied, there are not much study about the nevi at 18-25 years old age group. The aim of this study is to determine the clinical and dermoscopic features of melanocytic nevi in Turkish young people with 18–25 years-old. Methods: A total of 668 young people from students of Gulhane Military Medical Academy, Military Nurse School and Military Health Sergeant School and suitable patients of outpatient clinic of Gulhane Military Medical Academy Department of Dermatology were included in the study. A medical history of including age, sex, sunblock use, and sunburn asked. On clinical examination, we evaluated number of nevi, location of nevi and skin type. Nevi that are equal or greater than 3mm were examined dermoscopically, recorded and scored by using pattern analysis, ABCD total dermoscopic score, 7 point checklist, Menzies algorithm, 3 point checklist and CASH algorithm. Results: Totally 668 young people were physically examined in this study (268 of which were women and 400 of which were men). The most common skin phototype in both sexes was type 3 (91.6% of women, 85.25% of men). In 668 cases, a total of 3663 melanocytic nevi were determined. Mean number of nevi among cases were 5,4 ± 5,24. A total of 453 nevi which are equal or greater than 3 mm were examined dermatoscopically. The most common localization of nevi was on the head and neck region (n=144; 31.8%), followed by anterior trunk and abdomen (n=128; 28.3%), back (n=122; 26.9%) and extremities (n=45; 9.9%). The most common dermatoscopic global feature was the globular pattern (n=135; 29.8%), followed by reticular pattern (n=88; 19.4%), and cobblestone pattern (n=64; 8.8%). The correlations between 5 dermoscopic algorithm scores were done statically. Except the correlation between 7-point checklist and total CASH score(p=0,052 r=0,091), all algorithms were correlated with each other. Conclusion: Different dermoscopic algorithms can be used together in routine to investigate the melanocytic nevi for valuable professional follow . This is the one of the rare studies about the characteristics of melanocytic nevi at this age group and lays the foundation for future studies that will elucidate the relationship between nevi, dermatoscopic pattern and the other factors in a population-based cohort.