Abstract
Background: Air pollution causes severe damage to the skin but is less recognized in this context than UV radiation. It has been shown that particulate matter with a diameter less than 2.5 micrometers (PM2.5), a major component of air pollution, induces skin damage partially through overproduction of reactive oxygen species (ROS). Ascorbic acid (vitamin C) is a known antioxidant that may protect the skin from pollution and UV. However, ascorbic acid is easily degraded during storage. This study aimed to evaluate the efficacy of ascorbic acid and its more stable derivatives, as well as a capsulated ascorbic acid–containing serum, against PM2.5- and UV-induced ROS overproduction.
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