Abstract
In Tumor microenvironment, the anti-inflammatory Tumor associated macrophages (TAMs) promot angiogenesis, tumor growth, invasion, and metastasis. MALAT1 and HOTAIR are promising oncogenic lncRNAs. CD80 and Mesothelin (MSLN) are over expressed in breast cancer (BC). Our previous data showed MSLN overexpression upon silencing MALAT1 in BC. This study investigate the immunomodulatory role of HOTAIR and MALAT1 in TAMs of BC patients.
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Schedule a callMore From: Annals of oncology : official journal of the European Society for Medical Oncology
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