173P What to expect from NCCN BRCA testing criteria: A retrospective cohort analysis

Abstract

Approximately 5-10% of breast cancer patients have hereditary causes and since the frequency of mutation in these genes is rare, it is not recommended to investigate mutations in every patient with breast cancer. NCCN recommends to examine the BRCA genes for mutation in certain patient groups diagnosed with breast cancer. The aim of this study is to determine the possibility of detecting BRCA mutation in Turkish breast cancer patients based on NCCN criteria.