Abstract
Malignant pleural and peritoneal mesothelioma are rare malignancies with unacceptable poor prognosis and limited treatment options. The genomic landscape of these diseases is mainly characterized by loss of tumor suppressor genes and mutations in DNA repair genes. Currently, data from next-generation sequencing (NGS) of mesothelioma tumors is restricted to a limited number of cases; moreover, data comparing molecular features of mesothelioma from pleural and peritoneal origin with NGS are lacking.
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