Abstract
Applying digital subtraction technique on image data, collected during chest fluoroscopy, we compared radiological/ measured tidal ventilation volumes with volume values obtained using standard pneumotachometry. Three white NZ rabbits were studied, while ventilated on volume-controlled ventilator. Changes in X-ray transmittance due to tidal ventilation were calculated for whole chest area and for various regions of interest. There were highly significant linear correlations (p<0.001, r=0.97-0.99) between radiologically measured tidal volumes and those measured using pneumotachometry. When changes caused by tidal ventilation in various regions of interest were studied, the correlations remained highly significant, although with lower r values. We conclude that digital subtraction chest fluoroscopy can be used in quantitative estimation of tidal ventilation. It may also allow to evaluate regional variations in ventilation.
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