Abstract
Cytomegalovirus (CMV) is the most clinically relevant infectious agent in heart transplant (HT) recipients. Although antiviral agents used in a prophylaxis strategy seem superior to a pre-emptive approach to reduce CMV burden and its consequences, the impact of the additional anti-CMV effect of everolimus (EVE) on the benefit of antiviral prophylaxis is currently unexplored. In this study we analyzed the interaction of anti-CMV strategy and the use of EVE or mycophenolate (MMF) on the occurrence of CMV events in de novo HT recipients.
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