Abstract
Palatogenesis and tongue development are complex processes occurring during the formation of the craniofacial region in vertebrate embryos. Palate development comprises multiple events, including patterning of the palatal shelves, palatal growth, elevation, and fusion. A tightly regulated network controls these processes. Tongue development is also highly regulated and involves the interaction between myogenic progenitors and the surrounding cranial neural crest-derived mesenchyme, as well as events controlled intrinsically in these two compartments. Here we summarize major advances in the understanding of both palate development and tongue myogenesis from a molecular perspective.
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