17 - Organic biosensors and bioelectronics

Abstract

The interfacing of biomaterials to electronic devices is one of the most fascinating challenge in fundamental studies as well as in the development of ultrasensitive biosensors. Important aspects connected to the field of biosensors based on electrolyte-gated organic transistors are discussed. An overview of bioelectronic thin-film transistors is herein provided along with the strategies for the deposition of the biorecognition elements on the biosensor’s transducer surface. Among the different configurations of biosensors based on thin-film transistors, particular attention is paid to the electrolyte-gated organic transistors’ based biosensors. The operation mechanism is herein highlighted, along with the definition of the main analytical figure of merits. In the last part, different electronic biosensors based on electrolyte-gated organic transistors are presented. Specific applications such as proteins detection are also discussed.