Abstract
S 20TH ANNUAL CONFERENCE OF INASL, MARCH 2–4, 2012 S14 © 2012, INASL A b tra ts as well as on those with EDS (P < 0.0001). Significant correlation existed between PHES and both the sleep parameters of PSQI (r = −0.518, P < 0.0001) as well as ESS (r = −0.383, P < 0.0001), implying independently strong correlation between MHE status and the presence of night-time sleep disturbance and daytime somnolence among cirrhotics. Significant correlation existed between PSQI and ESS and the various scales and component scores of SF-36 (v2) signifying the negative impact of sleep disturbance on the HRQOL. Conclusion: Both nighttime sleep disturbance and EDS have significant relation with the neuropsychiatric impairment in patients of cirrhosis and are significantly associated with the observed impairment in HRQOL.
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