Abstract
PCa is well known to be an androgen-dependent disease. However, estrogens and estrogen receptors alpha and beta (ERα and ERβ) also play an important role in PCa progression. All types of receptors share similar structure and can be activated by same ligands. As so, relative amounts of all receptor types may be important in predicting overall response to therapy, including androgen deprivation. We aimed to assess possible correlations between ERα, ERβ and androgen receptor (AR) expression in clinical PCa samples.
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