168: Transcatheter aortic valve implantation in patients with small body size

Abstract

The purpose of this study was to evaluate the efficacy and safety of transcatheter aortic valve implantation (TAVI) in patients with small body size (SB). Clinical outcome of TAVI in patients with SB remains unclear. Between October 2006 and November 2011, 424 patients with severe aortic stenosis undergoing TAVI were evaluated. The cohort with small body surface area of <1.75 m 2 was defined as the “SB group” (n=215) and the rest of the cohort with large body-size as the “LB group” (n=209). In the SB group, the aortic annulus and femoral artery diameter were significantly smaller (23.0±1.86 vs 24.3±1.94 mm, p <0.001; 7.59±1.06 vs 8.29±1.34 mm, p <0.001, respectively). The logistic EuroSCORE was similar between the groups (22.5±10.4 vs 23.4±12.0, p=0.433). Equivalent device success (91.2 vs 91.4%, p=0.935) and 30-day survival rates (85.1 vs 87.6%, p=0.464) were achieved in both groups. Vascular complications were significantly higher in the SB group (13.0% vs 4.3%, p=0.002). Similar post-procedural mean pressure gradient was achieved in both groups (10.2±4.3 vs 11.0±4.6 mmHg, p=0.119). Kaplain-Meier survival analysis revealed no significant difference in the mid-term survival between groups (log-rank p=0.642). TAVI in patients with SB resulted in similar clinical outcomes with effective post-procedural hemodynamics compared with LB. Care should be taken to avoid vascular complication in patients with SB.