166 Itch and skin inflammation at insulin pump sites in patients with type 1 diabetes

Abstract

Skin reactions are common with insulin pump use and can impact adherence and the ability to sustain pump therapy. Little is known about the skin changes with pump use. We investigated itch and mediators of itch at pump sites in a cohort of patients with type 1 diabetes (n=31). Skin biopsies from current and recently used pump sites were compared to control sites where a pump had never been used. Samples were analyzed by histology and tissue histamine. Ninety-four percent (29/31) of patients described itch at pump sites.