Abstract

SBI has been used as component of systemic antitumor therapy in the management of 187 advanced cancer patients with Hodgkin's disease (76), lung cancer (70), breast cancer (32) and others (9). The patients were treated at the 15 MeV linear accelerator; 1.5 Gy/min with no shielding was employed. Single dose 1–1.5 Gy to total dose 4–6 Gy (lung corrected) was given to the trunk midplane during 7–10 days in Hodgkin's disease patients. Patients showed good immediate results: discontinuance of B-symptoms (fever, night sweats), diminution of lymph nodes, decrease and disappearance of lung involvement. A dose of 1. 8 Gy to total dose 19 Gy (N = 11) given every day during 2–3 weeks. There was regression of lung involvement, decrease and disappearance of bone pain, diminution of lymph nodes, regression of hepar involvement. SBI is an effective method of radiotherapy in chemotherapy-resistant cases.

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