162 Comparative study of previous pregnant women of COVID-19 care at the intensive care unit in a west hospital in the Western Amazon, In the years 2020/2021

Abstract

Introduction: Novocoronavirus contamination in Brazil has been increasing significantly.In December/2020 there was an increase in deaths and new infections, with the appearance of the P1 variant in the city of Manaus-Amazonas.This new variant, when compared with the hospitalization and evolution of pregnant women and women of the previous year, seems to be associated with greater virulence and the development of a clinical picture even more severe than the strain that circulated in the first wave in Western Amazonia. Objective: To report the cases of pregnant women with COVID-19 attended in the ICU in the first three months of 2021 compared to the year 2020. Method: Comparative study of data from the intensive care unit of a hospital in the western Amazon. Results: In the period from March to December 2020, 14 patients were treated at the ICU: 08 pregnant women and 06 puerperal women, of whom 07(50,0%) evolved with the need for orotracheal intubation and 03(21,42%) died. In the period from January to March 2021, there were 27 hospitalizations:10 pregnant women,17 puerperal women with COVID-19,of these 22(81,4%) orotracheal intubation,09(33,3%) died,11(40,0%) they were discharged,07(25,9%) are still hospitalized with severe conditions. Conclusion: The increase in the severe condition in pregnant women and women who have recently given birth with COVID-19 may be related to a greater virulence of new strains and / or variants of the strain that circulated in the first wave in 2020. It is important to consider that further studies should be carried out in this group of patients and greater genomic surveillance of the virus, in order to identify the infection as early as possible, and to establish protocols for adequate clinical management