Abstract
Airborne particulate matter can cause oxidative stress, inflammation, and premature skin aging. Marine plants such as Ecklonia cava Kjellman contain high amounts of polyphenolic antioxidants. The purpose of this study was to examine the antioxidative effects of E. cava extract in cultured keratinocytes exposed to airborne particulate matter with a diameter of
Highlights
Air pollution of natural and artificial origins presents a significant concern
When human HaCaT keratinocytes were treated with Particulate matter of less than 10 micrometers (PM10) (3 to 100 μg mL−1 for 48 h), their viability decreased in a dosedependent manner
The cells were treated with E. cava extract at 25, 50, 75, or 100 μg mL−1 and exposed to 100 μg mL−1 PM10 for 48 h
Summary
Air pollution of natural and artificial origins presents a significant concern. Because PM10 is too small to be caught in the nasal cavity and bronchial cilia, it can deeply penetrate the lungs and cause inflammation, asthma, chronic bronchitis, and airway obstruction [3, 4]. PM10 can infiltrate blood vessels and circulate throughout the body, which may cause cardiovascular and cerebrovascular diseases [5]. The particles can attack eyes, causing various diseases such as allergic conjunctivitis and dry eye syndrome [6]. PM10 penetrates the skin through pores and other inflamed sites, aggravating skin diseases such as atopic dermatitis, acne, and psoriasis [7]. Airborne particles are associated with premature skin aging [8]
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