159P - The relation between obesity and cancer of gastrointestinal tract in Korea: The data from Statistic Korea between 2001 and 2016

Abstract

BackgroundObesity is a risk factor for several cancer. In Korea, prevalence of obesity has increased and incidence of several cancers of gastrointestinal (GI) tract, such as colon cancer and rectal cancer have increased. The aim of this study was to evaluate the association between obesity prevalence and cancer incidence of gastrointestinal tract in Korea adults. MethodsThe data were collected from the webpage of Statistic Korea, where the incidence of GI tract cancer between 2001 and 2016 was obtained from National Cancer Center, and the prevalence of obesity between 2001 and 2016 was obtained from National Health and Nutrition Examination Survey. The obesity was defined as BMI ≥25 kg/m2 among adults ≥30 years old. The association between obesity and cancer of GI tract was calculated by using linear regression analysis. ResultsIn men, prevalence of obesity was significantly associated with esophageal cancer (β: 0.176, P = 0.001), colon cancer (β: 2.034, P = 0.013), rectal cancer (β: 1.305, P = 0.035), gallbladder cancer and other biliary tract cancer (β: 0.712, P < 0.0001), and pancreatic cancer (β: 0.717, P < 0.0001). But, gastric cancer (β: 1.396, P = 0.076) and liver cancer (β: 0.122, P = 0.496) were not associated with obesity prevalence (Table) In women, incidence of GI tract cancer was not associated with obesity prevalence.Table159P Linear regression between obesity and GI cancer in men adultsTableCancerBeta coefficient95% CIP valueEsophageal cancer0.1670.092 - 0.2410.001Gastric cancer1.396-1.76 - 2.9680.076Colon cancer2.0340.535 - 3.5330.013Rectal cancer1.3050.114 - 2.4950.035Liver cancer0.122-0.262 - 0.5060.496Gallbladder and other biliary tract cancer0.7120.498 - 0.927<0.0001Pancreatic cancer0.7170.434 - 0.999<0.0001 ConclusionsIn Korean adults, incidence of some GI tract cancer seems to be associated with obesity prevalence. Legal entity responsible for the studyThe authors. FundingHas not received any funding. DisclosureAll authors have declared no conflicts of interest.