15918 Effects of a topical growth factor regimen after preelected cosmetic facial injection procedures

Abstract

Americans spent $16.5 billion on surgical and minimally invasive cosmetic procedures in 2018, a 4% increase from the previous year1. This reflects how seeking treatments that address esthetics remains an important priority for patients. Skincare can also help address facial esthetics by targeting skin quality. However, there are limited studies assessing the effects of skincare following cosmetic facial injection procedures (CFIP). To assess the efficacy and tolerability of a novel regimen (NR; growth factors, antioxidant dual serums, and hyaluronic acid-based serum), following pre-elected facial neuromodulator and hyaluronic acid dermal filler treatments, a 16-week, multicenter study was conducted. 18 female subjects aged 34-65 with Fitzpatrick skin types II-V completed. All subjects pre-elected to receive CFIPs at baseline, and continued their regular skincare through week 4 (phase 1). During phase 2, week 4-week 16, subjects applied NR twice daily. Investigator grading, questionnaires and photography were conducted at all visits (baseline and weeks 4, 8, 12, 16). Preelected CFIPs and regular skincare provided significant improvements in overall photodamage, tactile roughness, skin tone evenness and fine/coarse lines during phase 1 (all P ≤ .05; paired t test). During phase 2, use of NR provided additional continued significant improvements vs week 4 for overall photodamage, tactile roughness, radiance and skin tone evenness at weeks 8, 12 and 16 (all P ≤ .002; paired t test). There was high subject satisfaction and patients tolerated the topical regimen well. Our study demonstrates that high-grade medical skincare after cosmetic facial injections improves skin quality and can be a useful adjunct to enhance cosmetic procedures.