Abstract
Cisplatin nephrotoxicity results from renal accumulation of cisplatin via organic cation transporter 2 (OCT2). Since proton pump inhibitors (PPI) are known to inhibit OCT2 activity, it was thought that the combined use of PPI and cisplatin could prevent nephrotoxicity. In this study, we aimed to evaluate the effect of PPI use on nephrotoxicity in patients with head and neck cancer who received concurrent cisplatin with radiotherapy.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
