Abstract

Angiographically detectable transplant coronary artery disease (TxCAD) prevalence increases continuously after heart transplantation and reaches 50% at 5 years. Even annual coronary angiographic (CA) screenings often fail to detect TxCAD before clinical events. Longitudinal and radial systolic wall motion peak velocities (Sm) at the left ventricular (LV) basal regions are the echocardiographic parameters that show the greatest differences between patients with and without TxCAD, long before any evidence of regional wall motion disturbances or relevant LVEF changes emerges.

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