Abstract

Patients (n = 109) given fractionated radiotherapy of the abdomen were studied to compare the antiemetic efficacy of ondansetron (ond) with placebo. The patients recorded daily emesis, nausea and bowel habit and graded weekly symptoms of nausea, vomiting, diarrhea and lack of appetite. The EORTC C30 questionnaire was completed. Sixty-seven percent of patients given ond had complete control of emesis compared with 45% of patients with placebo ( P P P P

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