Abstract

The Boston keratoprosthesis (Kpro) type 1 is the most common keratoprosthesis used in the world. However, there remain significant challenges with complications that can arise in the postoperative period related to the anterior and posterior segment, which can lead to complete no light perception. Patients with autoimmune disease (Stevens-Johnson syndrome, Mucus membrane pemphigoid, and severe chemical injuries) have a poorer prognosis. This chapter reviews the following common complications after Kpro implantation: retroprosthetic membrane formation, elevated intraocular pressure and glaucoma, endophthalmitis, retinal detachment, sterile vitritis, infectious keratitis, corneal melt or sterile keratolysis, and device extrusion. A multispecialty ophthalmology team is needed to adequately manage these complications.

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